Jurgen Klopp's side booked their place in the Carabao Cup semi-final midweek after an emphatic 5-1 victory over West Ham United at Anfield, but will now turn their attention back to the Premier League.
The Reds find themselves just a point off the Gunners and know a victory would ensure they are first at Christmas.
Liverpool played out a thrilling 2-2 draw with Mikel Arteta's men in this fixture last season, a game full to the brim with drama. Arsenal had taken a two-goal lead, but efforts from Mohamed Salah and Roberto Firmino earned the Reds a point - despite the former missing a second-half penalty.
Saturday's clash has the potential to be just as manic, so it's certainly not one you'll want to miss.
HOW TO WATCH LIVERPOOL VS ARSENAL ON TV
Luckily for those in the United Kingdom, Liverpool's clash with Arsenal will be broadcast live on Sky Sports. For those unable to catch the game on TV, it will be available to listen to on BBC Radio 5 Live.
In Australia, the game will be shown on Optus Sport, while fuboTV in Canada and Peacock in the United States will also be streaming the action.
DAZN, Viaplay and Sky Sports will be the main broadcasters in Europe, while those in South America will most likely be able to catch the game on Star+.
Much of Africa will be able to watch the game on SuperSport, while beIN Sports will be showing the game live in large parts of Asia.
Of course, match highlights will be available after the full-time whistle on LFCTV, while you can keep up to date with the action on the Anfield Watch socials.